Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the treatment of obesity and diabetes. While commonly administered by injection, semaglutide is also available in an oral tablet form.

Semaglutide tablets contain the same active pharmaceutical ingredient as injectable forms, but are formulated with an absorption enhancer to allow oral delivery. The tablets are typically taken once daily on an empty stomach with a sip of water, requiring a 30-minute wait before food or drink.